Intervention § Delivery of a leaflet (inclusive oral instruction of the leaflet: background information and step-by-step instruction in the s.c. injection technique) § Delivery of a manual (brief summary of the sequential steps of an s.c. injection) § Delivery of a kit (20 alcohol swabs, cotton swabs, and plasters) § Oral instruction in s.c. injection technique § Injection training into a “phantom” (injection pillow; PharmaDesign Inc., Warren, NJ, USA; delivered by Pfizer AG) § Instruction in the injection technique using a commercial video (CD-ROM or website) § (First) self-injection in the presence of a pharmacist (at patient’s individual injection time) § (First) injection administered by a pharmacist (ClinS-I: primary investigator; DailyS-I: trained community pharmacist) |